Developing new cancer therapies and improving the quality of patients’ lives is at the heart of everything we do. By focusing on novel first-in-class drug development, we aim to develop the therapies of the future. Our goal is to create effective therapies that provide meaningful and durable benefit to cancer patients.
Actively Recruiting Patients
Clinical trials are an essential part of discovering new cancer therapies and making them available to those in need. We are actively seeking patient volunteers for the following clinical trials:
Clinical Trial
RGX-104
This study evaluates the efficacy RGX-104, a novel oral small molecule immunotherapy candidate, as a single agent and in combination with nivolumab. Patients diagnosed with a wide range of conditions, including the following, may be eligible to participate in our clinical trial:
Clinical Trial
RGX-202
This study is designed to evaluate the therapeutic effect of oral RGX-202 administration as a single agent or combination therapy in patients with advanced gastrointestinal tumors. Patients diagnosed with any of the following malignant gastrointestinal tumors may be eligible to participate:
About RGX-104
About RGX-202
RGX-104 is an investigational small molecule immunotherapy that activates LXR, resulting in depletion of both myeloid-derived suppressor cells (MDSCs) as well as tumor blood vessels. MDSCs block the ability of T-cells and other cells of the immune system to attack tumors.
RGX-202 is a small molecule that suppresses gastrointestinal cancer growth by inhibiting a novel cancer metabolism pathway involved in supplying energy to cancer cells.