Rgenix is a privately-held clinical-stage biopharmaceutical company developing first-in-class drugs that target key pathways in cancer progression.

310 E 67th St, Suite 1-12‎ New York, NY
(646) 856-9261

Rgenix Is Now Inspirna

The future of cancer medicine inspired by RNA biology

Novel cancer pathways

Inspirna (formerly Rgenix) is a clinical-stage biopharmaceutical company developing first-in-class drug candidates that target key cancer pathways.

Our discovery platform

Our proprietary technology can be applied to virtually any type of cancer and has yielded novel therapeutic targets for several high unmet need malignancies.

Clinical proof of concept

RGX-104 is an oral immunotherapy that targets the immune system to block cancer progression.



RGX-104 is a novel oral small molecule immunotherapy in development for the treatment of solid tumors, including drug-resistant malignancies.



RGX-202 is an oral small molecule cancer metabolism inhibitor in development for the treatment of gastrointestinal cancers, including colorectal and gastric cancer.



RGX-019 is a monoclonal antibody that targets a key pathway that drives tumor progression and metastasis of several cancer types, including triple-negative breast cancer.


Clinical Trials

We are actively recruiting patients for phase 1 first-in-human, dose escalation and expansion studies of RGX-104 and RGX-202.


Our Science

Science underlying Rgenix’s technology and pipeline has been published in leading scientific journals.